Strategic Design of Alternative Methods to Reduce Animal Testing

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Basic Training: 12-13 September 2011
Advanced Training*: 14-15 September 2011
*Note: Basic course is prerequisite to register for advanced course

Download a Powerpoint presentation on new functionalities in Toolbox Version 2.0

Background
The QSAR Toolbox was developed under the aegis of OECD to facilitate the use of the category approach and QSAR methods to fill data gaps in classification and labeling.  Use of the Toolbox will save resources, reduce the need for animal testing, and greatly accelerate the hazard assessment process. 

The Toolbox provides the ability to:

• Make estimates of the relevant endpoints for single chemicals, linked to the CAS number or the chemical structure. Obtain summary information on the validation processes and results of the model so that the user can decide for which regulatory purpose the estimate can be used.
• Obtain a list of analogues for a chemical, together with their experimental, or estimated environmental, toxic or health effects.
• Obtain estimates for metabolite activation/detoxification information for the chemical.
• Interface with IUCLID 5 with ability for automated submission of estimated values for registration purposes

Who Should Take this Official Training?
QSAR Toolbox training is offered at two levels: Basic and Advanced.  The Basic Training Course, which requires some knowledge of chemical structure, provides an overview of the Toolbox databases, modeling system, and use of QSAR methods for managing data and modeling, plus a hands-on introduction to filling data gaps for hazard assessment.  The Advanced Training Course, for which the Basic Training Course is a prerequisite, is intended to provide the capability to make advanced hazard assessments for a wide variety of chemicals, along with documentation of the process in a form suitable for submission to regulatory agencies.

The Training Courses are designed for those charged with developing safety assessments for chemical manufacturers and distributors as well as for those charged with evaluating submitted assessments for new chemicals or those already in use in commerce.  Those interested in or kasyno poland conducting research on QSAR tools and database development would also find the training useful.

Who is Conducting the Training?
The International QSAR Foundation is coordinating the training courses with the Toolbox developer.  Instructors are selected from those who were original developers of the Toolbox. Limited follow-up assistance will be provided by the instructors, or trainees can subscribe to paid support services.  If you would like to see a training session in your area, contact the Toolbox Training Manager, Dr. Rosemarie Russo, at This e-mail address is being protected from spambots. You need JavaScript enabled to view it .

Fees and Requirements
Course registration fee for each course is €1770 (includes 18% VAT) for industry trainees and €1180 (includes 18% VAT) for government and university trainees.  This includes installation of the OECD Toolbox on each trainee’s laptop computer, all course materials, two lunches, coffee breaks, and a Course Certificate. 

Language of the course is English.  Trainees must provide their own laptop computers (recommended hardware requirements OS-Windows 2000, XP or newer; CPU: Pentium-4 at 2GHz or faster; RAM-1 GB; HDD- 8GB free hard drive space).  NOTE: UK and non-EU trainees should bring their own adaptor for the EU electrical plug.  Trainees make their own travel and lodging arrangements.  Registration is limited and is on a first-come first-served basis. A waiting list will be maintained in event of cancellation(s).  Registrants canceling with 30 days or more advance notice will receive a full refund of registration fee; canceling by fewer than 30 days is unrefundable. Venue for the training sessions is the Barcelona World Trade Center, located on the Mediterranean Sea at the end of the Barcelona Wharf in the historic center of Barcelona.  It is 15-20 minutes from the airport and easily reached by city bus and city metro.  Address: World Trade Center, Moll de Barcelona s/n, Edificio Sur, 1st floor, 08039 Barcelona; telephone 34 93 508 8000, http://www.wtcbarcelona.com/. 


How to Register
Local arrangements are being made by local coordinator Dr. Gemma Falcó Alay, REACH Monitor SLNE.  REACH Monitor is affiliated with the University of Barcelona, with activity in the field of toxicology, specially focused  on REACH regulation.  To register, please go to http://www.reachmonitor.com/index.php?lang=2&aptd=4&id=32 and complete the registration form for the specific course (BASIC and/or ADVANCED) you are planning to attend.  Payment is due upon notification of acceptance of  registration form and will be made by funds transfer to REACH Monitor.  Registration is not complete until payment is received.   Government/academic registrants must provide written proof of employer.

Questions?
Please direct questions to Dr. Rosemarie Russo, Training Coordinator, at This e-mail address is being protected from spambots. You need JavaScript enabled to view it .

High interest is expected for training on Toolbox Version 2.0,
being launched in October 2010, so early registration is encouraged

Background
The QSAR Application Toolbox was developed under the aegis of OECD to facilitate the use of the category approach and QSAR methods to fill data gaps in classification and labeling.  Use of the Toolbox will save resources, reduce the need for animal testing, and greatly accelerate the hazard assessment process.

The Toolbox provides the ability to:

• Make estimates of the relevant endpoints for single chemicals, linked to the CAS number or the chemical structure. Obtain summary information on the validation processes and results of the model so that the user can decide for which regulatory purpose the estimate can be used.
• Obtain a list of analogues for a chemical, together with their experimental, or estimated environmental, toxic or health effects.
• Obtain estimates for metabolite activation/detoxification information for the chemical.
• Interface with IUCLID 5 with ability for automated submission of estimated values for registration purposes

Who should take this official training?
QSAR Toolbox training is offered at two levels: Basic and Advanced.  The Basic Training Course, which requires some knowledge of chemical structure, provides an overview of the Toolbox databases, modeling system, and use of QSAR methods for managing data and modeling, plus a hands-on introduction to filling data gaps for hazard assessment.  The Advanced Training Course, for which the Basic Training Course is a prerequisite, is intended to provide the capability to make advanced hazard assessments for a wide variety of chemicals, along with documentation of the process in a form suitable for submission to regulatory agencies.

The Training Courses are designed for those charged with developing safety assessments for chemical manufacturers and distributors as well as for those charged with evaluating submitted assessments for new chemicals or those already in use in commerce.  Those interested in or conducting research on QSAR tools and database development would also find the training useful.

Who is conducting the training?
The International QSAR Foundation is coordinating the training courses with the Toolbox developer.  Instructors are selected from those who were original developers of the Toolbox. Limited follow-up assistance will be provided by the instructors, or trainees can subscribe to paid support services.  If you would like to see a training session in your area, contact the Toolbox Training Manager, Dr. Rosemarie Russo, at This e-mail address is being protected from spambots. You need JavaScript enabled to view it .

Fees and requirements
Course registration fee for each course is €1770 (includes 18% VAT) for industry trainees and €1180 (includes 18% VAT) for government and university trainees.  This includes installation of the OECD Toolbox on each trainee’s laptop computer, all course materials, two lunches, coffee breaks, and a Course Certificate.

Language of the course is English.  Trainees must provide their own laptop computers (recommended hardware requirements OS-Windows 2000, XP or newer; CPU: Pentium-4 at 2GHz or faster; RAM-1 GB; HDD- 8GB free hard drive space).  NOTE: UK and non-EU trainees should bring their own adaptor for the EU electrical plug.  Trainees make their own travel and lodging arrangements.  Registration is limited and is on a first-come first-served basis. A waiting list will be maintained in event of cancellation(s).  Registrants canceling with 30 days or more advance notice will receive a full refund of registration fee; canceling by fewer than 30 days is unrefundable.  Venue for the training sessions is not yet set, but will be near center of Barcelona.

How to register
Local arrangements are being made by local coordinator Dr. Gemma  Falcó Alay, REACH Monitor SLNE.  REACH Monitor is affiliated with the University of Barcelona, with activity in the field of toxicology, specially focused  on REACH regulation.  To register, please go to http://reachmonitor.org/index.php?lang=2&aptd=4&id=31 and complete the registration form for the specific course (BASIC and/or ADVANCED) you are planning to attend.  Payment is due upon notification of acceptance of  registration form and will be made by funds transfer to REACH Monitor.  Registration is not complete until payment is received.   Government/academic registrants must provide written proof of employer.

Questions?
Please direct questions to Dr. Rosemarie Russo, Training Coordinator, at This e-mail address is being protected from spambots. You need JavaScript enabled to view it .

We are pleased to announce the spring training in Barcelona, to be held April 26 - 27, 2010, for the basic training course and April 28 - 29, 2010, for the advanced training.  The Toolbox is available to the public as a free download from OECD. The International QSAR Foundation coordinas with OECD, the developer of the Toolbox, and local organizers to make training available on a cost-recovery basis. If you would like to serve as an organizer for training in your geographic area, please contact Dr. Rosemarie Russo, Training Coordinator, russo[at]qsari.org ' + contact_email + '') // ]]> . For more information on training in beautiful Barcelona, please visit the REACHMonitor website

We have now trained more than 100 scientists from Europe, Asia and the USA on OECD's QSAR Application Toolbox. The first training in the US was conducted in Baltimore, MD, on October 5 - 6, 2009 for the basic training course and October 7 - 8, 2009, for the advanced training workshop. The Toolbox is available to the public as a free download from OECD. The International QSAR Foundation coordinates with OECD, the developer of the Toolbox, and local organizers to make training available on a cost-recovery basis. If you would like to serve as an organizer for training in your geographic area, please contact Dr. Rosemarie Russo, Training Coordinator, at ' + contact_email + '') // ]]> russo[at]qsari.org.  Registration for the training was available through the International QSAR School developed by IQF.

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